Please see below for peer-reviewed articles about the effectiveness and safety of BHRT.
“Compared to placebo, women assigned to oral estrogen therapy improved significantly on measures of depression-dejection and anxiety-tension. The treatment group also showed a trend in improvement on measures of anger-hostility and memory recall of printed material.”
“Oral estradiol therapy was associated with less progression of subclinical atherosclerosis than was placebo when therapy was initiated within 6 years after menopause.”